In case of elevated CO2 blood levels, hypercapnic respiratory failure occurs as a consequence of the mechanical ventilation. Invasive lung-protective, based predominantly on low tidal volume, and non-invasive mechanical ventilations, can cause CO2 accumulation and consequent development of severe hypercapnia and respiratory acidosis.
Hypercapnic respiratory failure can therefore be preserved thanks to the use of extracorporeal techniques dedicated to CO2 removal and with the aim to:
- Facilitate invasive mechanical ventilation based on low tidal volume;
- Reduce CO2 accumulation, in case of non-invasive mechanical ventilation, and avoid invasive ventilation upgrade.