Diabetic foot syndrome is defined as the set of pathological manifestations directly related to the complications of diabetic disease involving the anatomical structures of the foot. It is a syndrome characterized by the interaction of chronic complications of diabetes, both micro and macroangiopathic, with an extremely important role in neuropathy.
Diabetic foot is particularly susceptible to the effects of complications resulting from peripheral neuropathy, vasculopathy and infectious processes.
Due to decreased blood flow, the onset of ulcerative lesions is facilitated. Skin ulceration in diabetic patients is classified according to the cause that caused the lesions to appear. The ulcer, if not cured, degenerates into deep ulcer, up to the gangrene and, in the terminal stage, needs amputation.
To date, treatment of diabetic foot syndrome involves the administration of drugs, revascularization treatments and plasmapheresis, with the aim of eliminating from the circulation all those substances that can compromise micro and macrocircle and, consequently, determine aggravation of the state of disease.