Plasmapher/Apherlungs is a simple multi-therapeutic platform, designed for the execution of multiple extracorporeal purification treatments:

  • Plasmapheresis (PEX)
  • Cascade Filtration (CF)
  • Double Filtration Plasmapheresis (DFPP)
  • Purification module
  • Hemoperfusion

The goal is to allow the purification of plasma or blood from multiple molecules that, by nature and / or concentration, are harmful to the body, for example in immune-mediated or autoimmune diseases, or the purification of the perfusion liquid for the modulation of the inflammatory response during ex-vivo organ reconditioning, in particular lungs.

Loading...
Plasmapher Apherlungs

Teraphies and treatments

Related Pathologies

Automatic and balanced reinfusion of replacement solutions.

Plasmapher / Apherlungs platform allows the execution of Plasma Exchange treatments, which consist in the entire replacement of the patient’s plasma, through the administration of donor plasma and / or albuminate solution. This technique requires that the whole blood taken from the patient is separated, through plasma filter, into plasma and corpuscular elements, thanks to the exercise of a pressure on the membrane (TMP). The patient’s separate plasma is completely discarded and replaced with donor plasma and / or albuminate solution. This substitution solution is then mixed with the corpuscular part of the blood, then reinfused to the patient.

Plasmapher

Autologous plasma purification directly from cell separator.

Plasmapher/Apherlungs allows treatments to purify the patient’s plasma from target molecules and then the same plasma is reinfused to the patient. The Plasmapher/Apherlungs is connected directly to a cell separator for separating plasma from the corpuscular elements of the blood. The plasma obtained from the cell separator is conveyed to the Plasmapher/Apherlungs apparatus and semi-selectively purified from the target molecules. The purification is carried out using the EvafluxTM fractionators. Plasmapher/ Apherlungs automatically manages the regenerations of the fractionators filters, limiting the operator’s interventions

Plasmapher CF

Cascade filtration summary:

  • Minimally invasive
  • Automatic regeneration of the fractionator filter
  • Scoagulation with citrate or heparin
  • Less infections and autoimmune reactions
  • Reduced drug depletion
  • Semi-selective removal of target molecules
  • Reinfusion of purified autologous plasma (Saving plasma albumin levels)
Evaflux filters

Autologous plasma purification directly from the patient.

The Plasmapher/Apherlungs system allows the execution of plasma purification treatments of the patient from target molecules, after which, the same plasma, is reinfused to the patient.

Plasmapher/Apherlungs is directly connected to the patient and the plasma is separated from the corpuscular elements of the blood by the use of plasma filter. Following separation, the same plasma is conveyed into an Evaflux fractionator filter, which is dedicated to semi-selective removal of target molecules.
The equipment automatically manages the regenerations of the fractionators filters, keeping the performance unchanged throughout the treatment and limiting the operator’s interventions.

DFPP

DFPP in summary:

  • Automatic fractionator filter regeneration
  • Less infections and autoimmune reactions
  • Reduced depletion of drugs
  • Semi-selective removal of target molecules
  • reinfusion of purified autologous plasma (Saving plasma albumin levels)
Evaflux filters

In isolation

Thanks to the presence of a peristaltic pump able to work at variable flows up to a maximum of 400 ml/min, Plasmapher/Apherlungs is also designed to perform haemperfusion treatments with sorbent cartridges dedicated to whole blood adsorption of molecules responsible for the development of differents pathologies, including CytoSorb ®

Plasmapher

The PURIFICATION module arises from the possibility of applying aphaeretic techniques in complex clinical scenarios, such as severe cardiac and/or respiratory failures supported by the use of extracorporeal circulation systems, such as ECMO (Extracorporeal Membrane Oxygenation). In these cases, given the critical clinical picture of the treated patients and the invasiveness of the extracorporeal circuits, it is preferable to implement blood purification techniques with dedicated sorbent cartridges by directly inserting the system in parallel to the main circuit to which the patient is already connected, thus avoiding a direct connection of the equipment to the patient. This is possible thanks to the presence of a peristaltic pump able to work with variable flows up to a maximum of 400 ml/min.

In Parallel with ECMO circuit

Plasmapher/Apherlungs can be connected in parallel to an ECMO circuit for the execution of haemoperfusion treatments with sorbent cartridges dedicated to adsorption, including CytoSorb ®

ApherCap HP ECMO

The connection of the Plasmapher/ pherlungs system in parallel to a high-flow circuit is also used for purification treatments during ex-vivo organ reconditioning, in particular for lungs or abdominal organs. The goal is to purify the perfusion fluid from specific inflammatory factors that are able to condition the suitability for transplantation and any complications that may arise post-transplantation.

Do you need more information?

Contact us